Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants
نویسندگان
چکیده
منابع مشابه
Action of brain-derived neurotrophic factor on function and morphology of visual cortical neurons
Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...
متن کاملAction of brain-derived neurotrophic factor on function and morphology of visual cortical neurons
Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...
متن کاملHuman platelets contain brain-derived neurotrophic factor.
Neurotrophic support to peripheral sensory neurons is provided by 2 factors of related sequence, NGF and brain-derived neurotrophic factor (BDNF). NGF is present in peripheral target tissues, while BDNF has only been reported in the CNS. We now report the biological characterization and molecular cloning of a cDNA for BDNF from human platelets. BDNF in human platelets has biological activities ...
متن کاملBrain-derived neurotrophic factor:
Dekan Summary BDNF (brain-derived neurotrophic factor) plays an important role in neuronal survival, growth and maintenance of several neuronal systems, serves as neurotransmitter modulator and participates in plasticity important for learning and memory. BDNF is widely expressed in the CNS, beginning early in development and extending throughout life. In the mammalian brain, it is most abundan...
متن کاملS100B Protein, Brain-Derived Neurotrophic Factor, and Glial Cell Line-Derived Neurotrophic Factor in Human Milk
BACKGROUND Human milk contains a wide variety of nutrients that contribute to the fulfillment of its functions, which include the regulation of newborn development. However, few studies have investigated the concentrations of S100B protein, brain-derived neurotrophic factor (BDNF), and glial cell line-derived neurotrophic factor (GDNF) in human milk. The associations of the concentrations of S1...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2013
ISSN: 0307-0565,1476-5497
DOI: 10.1038/ijo.2013.221